Does a sinner know how sinful sin is? Many do not, but instead live in sin the way a fish lives in water. Take a sinner out, and he flops back into it. But in regeneration, this natural man–a sinner–dies and is born again as a Christian. Now, he lives in an environment of righteousness. A Christian can no longer live in sin, no more than a reptile could live underwater.
The Gospel calls for a radicalized people willing to die for it. Would you rather die than get mad, get drunk, or fornicate? Would you rather die than commit any sin? Are you giving up your life right now to the work of the Gospel?